1.

COVID-19 Readiness | COVID-19 and Coronavirus Research

… email ordering-de@origene.com with order related queries info-de@origene.com: EU related technical queries What COVID19-related products do OriGene offer? In relation to COVID19 research, OriGene offers a comprehensive tool box for ACE2, Furin, Spike protein (S-Protein) and N-Protein. Browse OriGene Products for COVID-19 OriGene will continue to partner with research communities…

/covid-19-readiness

2.

COVID 19 Gene: LZTFL1

… | Over-expression lysates | Lentiviral Particles | CRISPR Knockout Kits Tools for analyzing other COVID19 Genes References: 1 .Downes, D.J., Cross, A.R., Hua, P. et al. Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus. Nat Genet 53, 1606–1615 (2021). https://doi.org/10.1038/s41588-021-00955-3 …

/research-areas/covid-19/lztfl1-gene

3.

ACE2: Receptor for COVID-19 Invasion

… The recent outbreak of COVID-19 that started in Wuhan, China, has spread globally and caused major loss in human lives. The latest research has reported that ACE2 (angiotensin converting enzyme 2) is a functional receptor for COVID-19 to latch on and enter.View All COVID19 Products The coronavirus enters human cell through the interaction of virus Spike protein (S protein) and ACE2…

/blog/ace2-receptor-for-covid-19-invasion

5.

MolBio Tools for COVID-19 Research (SARS-CoV-2 infection)

COVID19 is caused by a newly identified coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early studies have shown SARS-CoV-2 attaches to the human cells through an interaction between viral “Spike” protein and human ACE2 receptors; after binding to the cell surface, the “Spike” protein gets cleaved by human TMPRSS2 protease to facilitate the entry of virus…

/research-areas/covid-19/molbio-tools

6.

Welcome to OriGene’s Test Your COVID-19 IQ Challenge Series Part Two

… We have been bombarded with information on COVID19 from the beginning of this year after the first case of COVID19 was diagnosed. I tried to keep up but with 6000+ papers published in the first two months that was hard to keep up. Then one day a 2nd grader asked a simple question ‘What is COVID19’? I tried to explain the disease, symptoms and causes but failed to come up with a…

/blog/covid-19-iq-challenge-2

7.

Welcome to OriGene’s Test Your COVID-19 IQ Challenge Series Part One

… We have been bombarded with information on COVID19 from the beginning of this year after the first case of COVID19 was diagnosed. I tried to keep up but with 6000+ papers published in the first two months that was hard. Then one day a 2nd grader asked a simple question ‘What is COVID19’? I tried to explain the disease, symptoms and causes but failed to come up with a simple answer…

/blog/covid-19-iq-challenge-1

8.

SARS-CoV-2 (2019-nCoV) Research Tools

… Tools to Investigate SARS-CoV-2 Infection Antibodies | [TA814512&Neutralizing Antibodies] | ELISA | Molecular Biology Reagents | Viral Proteins | Viral Mutants COVID-19 is caused by the coronavirus SARS-CoV-2, also called 2019-nCoV. The viral spike (S) protein - host cell ACE2 receptor interaction is key to a successful infection of the host cell…

/research-areas/covid-19

9.

Cytokine-Storm

COVID19 pandemic has stormed the world like no other storm/cyclone and some patients with COVID-19 just crash suddenly. These patients often present with a Multiple-Organ-Failure along with hypercytokinaemia, a result of the Cytokine Storm. A Cytokine Storm is an excessive release of proinflammatory cytokines in response to an infection. Recent…

/research-areas/cytokines/cytokine-storm

10.

OriGene Blog

…-recognizing clones. These are important to provide a complete TCR repertoire to fight against pathogens and may involve the... Read more... Welcome to OriGene’s Test Your COVID-19 IQ Challenge Series Part Two Jul 01, 2020 We have been bombarded with information on COVID19 from the beginning of this year after the first case of COVID19 was diagnosed. I tried to keep up but with 6000+ papers published…

/blog

11.

Cytokines

… respiratory distress syndrome (ARDS) and infectious diseases. Cytokines in COVID19 pathogenesis Recently, cytokines have been shown to play a vital role in COVID 19 pathogenesis. In some patients, SARS-CoV-2 infection results in an excessive rapid release of inflammatory cytokines, an event described as ‘Cytokine…

/research-areas/cytokines

12.

Expression cDNA Clones Enable You To Be More Productive in Research

… – Express proteins with a fusion tag for easy detection and purification Untagged cDNA clone – Express native proteins COVID19 cDNA clones – Express the virus protein and human cell receptors, activators et al When you purchase 3 or more any of the cDNA expression plasmids (lentiviral particles excluded), you will receive a $20 Amazon® gift card. Limited time offer…

/promotions/expression-cdna-clones-enable-you-to-be-more-productive-in-research

13.

Immuno-Oncology Targets & Research Tools

… [1]. Immuno-stimulatory cytokines that help the fight against cancer IFN-α IL-2 IL-10 IL-12 GMCSF Immunosuppressive cytokines in cancer therapy TNFα TGF-β CSF-1 Learn about Cytokines and its role on other diseases Get list of references, videos related to COVID19 and cytokines…

/research-areas/immuno-oncology

14.

TrueMAB® Monoclonal Antibodies - An Antibody Olympic Champion

… structures. These antibodies are great tools for immunoassays that are sensitive to protein conformations such as IF, IP, IHC, Flow, ELISA, antibody arrays, and more. You may learn more about our extensive antibody portfolio. Be a Part of Our Antibody Olympics Campaign We understand that the 2020 Summer Olympics is postponed to summer of 2021 due to the ongoing CoVID-19 pandemic, but we still want…

/promotions/antibody-olympics

15.

ACE2: A predictor of infectability in SARS-Cov-2

… catalytic domain, a junctional segment of the collectrin domain, a peptidase cleavage site, a TM domain, and a short cytoplasmic tail. It’s theoretical molecular weight: 92 kDa.The encoded protein is a functional receptor for the spike glycoprotein of the human SARS-CoV-2 (Covid-19). Fig 1. ACE2 Structure Fig 2. Block diagrams of the angiotensin-converting enzyme 2…

/blog/ace2-infectability-in-sars-cov-2